PE Risk & Treatment Tool
Based on 2026 AHA/ACC PE guidelines
1
2
3
4
5
Step 1
Incidental and asymptomatic PE?
Step 2
Hemodynamic status
Step 3
PESI Score
Age
Total PESI Score
Enter age to calculate
0
Class B
Clot location
Class C
RV dysfunction and biomarkers
RV dysfunction present?
RV Dysfunction Reference
RV/LV >0.9
TAPSE <1.7 cm
TDI S′ <9.5 cm/s
TR velocity ≥2.9 m/s
Class D
Incipient cardiopulmonary failure
Transient hypotension?
Definitions
D1
SBP <90 mmHg or decrease >40 mmHg lasting <15 minutes, or hypotension responsive to intervention without persistent end-organ hypoperfusion.
SBP <90 mmHg or decrease >40 mmHg lasting <15 minutes, or hypotension responsive to intervention without persistent end-organ hypoperfusion.
D2
Normotensive shock with RV failure and evidence of hypoperfusion despite preserved systemic blood pressure.
Normotensive shock with RV failure and evidence of hypoperfusion despite preserved systemic blood pressure.
Class E
Cardiopulmonary failure
Treatment
Anticoagulation
DOAC preferred over warfarin
LMWH preferred over UFH for C1–E1
APS: warfarin
Pregnancy: LMWH or UFH
Persistent symptoms >3 months: evaluate for CTEPD