Aortic Stenosis

TTE Suspicious for AS Assess velocity/gradient LOW-GRADIENT AS Vmax < 4 m/s, ΔPm < 40 mmHg HIGH-GRADIENT AS Vmax ≥ 4 m/s, ΔPm ≥ 40 mmHg Assess AVA High flow status excluded AVA ≤ 1.0 cm² AVA > 1.0 cm² No Yes Moderate AS Exclude measurement errors Severe high-gradient AS Define whether high flow is reversible Not reversible Reversible Severe AS Re-assess at normal flow Define flow status (SVi) Low flow (SVi ≤35) Normal flow (SVi >35) Severe AS unlikely Assess LVEF LVEF <50% LVEF ≥50% Dobutamine echo Integrated approach Flow reserve present No flow reserve Pseudosevere AS or true severe AS Calcium score by CT
AS Severity Grading
Parameter Mild Moderate Severe
Mean gradient (mmHg) <20 20–39 ≥40
AVA (cm²) >1.5 1.0–1.5 ≤1.0
Dimensionless index (LVOT VTI / AV VTI) >0.50 0.25–0.50 <0.25

AS Calculator

Severe AVA ≤1.0 cm² or DI <0.25 | Low flow SVI <35 mL/m² | Low gradient <40 mmHg | Reduced EF <50%

  • PLAX view
  • Zoom on the aortic valve and LVOT
  • Timing: Mid-systole (valve open)
  • Measure inner-edge to inner-edge
  • LVOT Area = 0.785 × (LVOT diameter)²

Represents forward stroke flow before the stenotic valve.

  • Apical 5-chamber or 3-chamber
  • PW doppler
  • 0.5–1.0 cm below the aortic valve

Measures velocity through the stenotic orifice

  • CW Doppler
  • Use multiple windows:
    • Apical 5-chamber
    • Apical 3-chamber
    • Right parasternal
    • Suprasternal notch
  • Use the window with the highest reproducible velocity
  • Trace the full systolic envelope
  • Peak velocity (Vmax)
  • Mean gradient
  • AV VTI

AVA = (LVOT Area × LVOT VTI) ÷ AV VTI


DI = LVOT VTI ÷ AV VTI

  • ≤ 0.25 = Severe
  • 0.25–0.50 = Moderate
  • 0.50 = Mild

Echo uses the Bernoulli equation:

  • ΔP = 4V²
    • Peak gradient = highest instantaneous pressure difference
    • Mean gradient = average pressure difference across systole

Stroke Volume = LVOT Area × LVOT VTI

  • Index to BSA → SVI
  • Low flow if:
    • SVI < 35 mL/m²
    • Low flow can cause low gradients even if valve is truly severe